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Cardiovascular Quality and Outcomes

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Circulation: Cardiovascular Quality and Outcomes Topic Review

Most Important Outcomes Research Papers on Cardiac Arrest and Cardiopulmonary Resuscitation

Karthik Murugiah, Serene I. Chen, Kumar Dharmarajan, Sudhakar V. Nuti, Brian Wayda, Abbas Shojaee, Isuru Ranasinghe, Rachel P. Dreyer
and for the Editor
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https://doi.org/10.1161/CIRCOUTCOMES.114.000957
Circulation: Cardiovascular Quality and Outcomes. 2014;7:335-345
Originally published March 18, 2014
Karthik Murugiah
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Serene I. Chen
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Kumar Dharmarajan
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Sudhakar V. Nuti
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Brian Wayda
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Abbas Shojaee
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Isuru Ranasinghe
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Rachel P. Dreyer
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  • Article
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Jump to

  • Article
    • Introduction
    • Epidemiology of Cardiac Arrest and Its Outcomes
    • Survival Trends in Pediatric In-Hospital Cardiac Arrests: An Analysis From Get With The Guidelines–Resuscitation
    • Nationwide Improvements in Survival From Out-of-Hospital Cardiac Arrest in Japan
    • Post-Cardiac Arrest Mortality Is Declining: A Study of the US National Inpatient Sample 2001 to 2009
    • Association Between a Hospital’s Quality Performance for In-Hospital Cardiac Arrest and Common Medical Conditions
    • Impact of Changes in Resuscitation Practice on Survival and Neurological Outcome After Out-of-Hospital Cardiac Arrest Resulting From Nonshockable Arrhythmias
    • Incidence, Causes, and Survival Trends From Cardiovascular-Related Sudden Cardiac Arrest in Children and Young Adults 0 to 35 Years of Age: A 30-Year Review
    • Advance Directives in Community Patients With Heart Failure
    • Predictors of Successful Cardiopulmonary Resuscitation
    • Chest Compression Alone Cardiopulmonary Resuscitation Is Associated With Better Long-Term Survival Compared With Standard Cardiopulmonary Resuscitation
    • Quantifying the Effect of Cardiopulmonary Resuscitation Quality on Cardiac Arrest Outcome: A Systematic Review and Meta-Analysis
    • Relationship Between Chest Compression Rates and Outcomes From Cardiac Arrest
    • Comparison of Outcomes After Use of Biphasic or Monophasic Defibrillators Among Out-of-Hospital Cardiac Arrest Patients: A Nationwide Population-Based Observational Study
    • Chest Compression-Only Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest With Public-Access Defibrillation: A Nationwide Cohort Study
    • Duration of Ventilations During Cardiopulmonary Resuscitation by Lay Rescuers and First Responders: Relationship Between Delivering Chest Compressions and Outcomes
    • Perishock Pause: An Independent Predictor of Survival From Out-of-Hospital Shockable Cardiac Arrest
    • Community Access to CPR and Automated External Defibrillators
    • A Crowdsourcing Innovation Challenge to Locate and Map Automated External Defibrillators
    • Dispatcher-Assisted Cardiopulmonary Resuscitation: Time to Identify Cardiac Arrest and Deliver Chest Compression Instructions
    • The Effectiveness of Ultrabrief and Brief Educational Videos for Training Lay Responders in Hands-Only Cardiopulmonary Resuscitation: Implications for the Future of Citizen Cardiopulmonary Resuscitation Training
    • Automated External Defibrillators Inaccessible to More Than Half of Nearby Cardiac Arrests in Public Locations During Evening, Nighttime and Weekends
    • Barriers and Facilitators to Learning and Performing Cardiopulmonary Resuscitation in Neighborhoods With Low Bystander Cardiopulmonary Resuscitation Prevalence and High Rates of Cardiac Arrest in Columbus, OH
    • Impact of Onsite or Dispatched Automated External Defibrillator Use on Survival After Out-of-Hospital Cardiac Arrest
    • Identifying Locations for Public Access Defibrillators Using Mathematical Optimization
    • Acute Post-Resuscitation Care
    • Is Hypothermia After Cardiac Arrest Effective in Both Shockable and Nonshockable Patients?: Insights From a Large Registry
    • Hypothermia in Comatose Survivors From Out-of-Hospital Cardiac Arrest: Pilot Trial Comparing 2 Levels of Target Temperature
    • Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest: Evaluation of a Regional System to Increase Access to Cooling Circulation
    • Implementation of the Fifth Link of the Chain of Survival Concept for Out-of-Hospital Cardiac Arrest
    • Disclosures
    • Footnotes
    • References
  • Info & Metrics
  • eLetters
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Introduction

Cardiac arrest is a common and treatable cause of death and disability. Each year ≈424 000 people experience emergency medical services (EMS)-assessed out-of-hospital cardiac arrest (OHCA) in the United States.1 The actual burden of OHCA is likely significantly higher because a substantial number go unassessed. In a prospective analysis of deaths in a US county, 5.6% of annual mortality was attributable to cardiac arrest.2 Many patients who suffer OHCA do not receive prompt cardiopulmonary resuscitation (CPR). Among those who receive CPR, a large number do not survive because of an inability to restore spontaneous circulation, or anoxic cerebral injury even after restoration of circulation. Nevertheless, when timely interventions are provided, a small proportion of patients (10.4% of all EMS-treated OHCA) recover to resume normal lives. The key therapeutic interventions that make the difference between life and death, metaphorically characterized as the 5 links in a chain of survival by the American Heart Association, include: (1) immediate recognition of cardiac arrest and activation of the EMS, (2) early CPR with emphasis on chest compression, (3) rapid defibrillation, (4) effective advanced life support, and (5) integrated postcardiac arrest care.3

Resuscitation science has undergone major advances since the origins of modern CPR >50 years ago.4 The field continues to be dynamic with emergence of new therapies such as therapeutic hypothermia5 and improvements in systems of care. However, many questions remain on issues such as optimum compression rate, efficacy of chest compression only CPR (CCCPR), dispatcher-assisted CPR, and benefits of postresuscitation measures such as hypothermia. A critical challenge also lies in the translation of resuscitation science into practice. To improve outcomes, each of the links in the chain of survival needs to be executed promptly and effectively. There remain several lacunae, which need to be overcome to develop an …

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Circulation: Cardiovascular Quality and Outcomes
March 2014, Volume 7, Issue 2
  • Table of Contents
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Jump to

  • Article
    • Introduction
    • Epidemiology of Cardiac Arrest and Its Outcomes
    • Survival Trends in Pediatric In-Hospital Cardiac Arrests: An Analysis From Get With The Guidelines–Resuscitation
    • Nationwide Improvements in Survival From Out-of-Hospital Cardiac Arrest in Japan
    • Post-Cardiac Arrest Mortality Is Declining: A Study of the US National Inpatient Sample 2001 to 2009
    • Association Between a Hospital’s Quality Performance for In-Hospital Cardiac Arrest and Common Medical Conditions
    • Impact of Changes in Resuscitation Practice on Survival and Neurological Outcome After Out-of-Hospital Cardiac Arrest Resulting From Nonshockable Arrhythmias
    • Incidence, Causes, and Survival Trends From Cardiovascular-Related Sudden Cardiac Arrest in Children and Young Adults 0 to 35 Years of Age: A 30-Year Review
    • Advance Directives in Community Patients With Heart Failure
    • Predictors of Successful Cardiopulmonary Resuscitation
    • Chest Compression Alone Cardiopulmonary Resuscitation Is Associated With Better Long-Term Survival Compared With Standard Cardiopulmonary Resuscitation
    • Quantifying the Effect of Cardiopulmonary Resuscitation Quality on Cardiac Arrest Outcome: A Systematic Review and Meta-Analysis
    • Relationship Between Chest Compression Rates and Outcomes From Cardiac Arrest
    • Comparison of Outcomes After Use of Biphasic or Monophasic Defibrillators Among Out-of-Hospital Cardiac Arrest Patients: A Nationwide Population-Based Observational Study
    • Chest Compression-Only Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest With Public-Access Defibrillation: A Nationwide Cohort Study
    • Duration of Ventilations During Cardiopulmonary Resuscitation by Lay Rescuers and First Responders: Relationship Between Delivering Chest Compressions and Outcomes
    • Perishock Pause: An Independent Predictor of Survival From Out-of-Hospital Shockable Cardiac Arrest
    • Community Access to CPR and Automated External Defibrillators
    • A Crowdsourcing Innovation Challenge to Locate and Map Automated External Defibrillators
    • Dispatcher-Assisted Cardiopulmonary Resuscitation: Time to Identify Cardiac Arrest and Deliver Chest Compression Instructions
    • The Effectiveness of Ultrabrief and Brief Educational Videos for Training Lay Responders in Hands-Only Cardiopulmonary Resuscitation: Implications for the Future of Citizen Cardiopulmonary Resuscitation Training
    • Automated External Defibrillators Inaccessible to More Than Half of Nearby Cardiac Arrests in Public Locations During Evening, Nighttime and Weekends
    • Barriers and Facilitators to Learning and Performing Cardiopulmonary Resuscitation in Neighborhoods With Low Bystander Cardiopulmonary Resuscitation Prevalence and High Rates of Cardiac Arrest in Columbus, OH
    • Impact of Onsite or Dispatched Automated External Defibrillator Use on Survival After Out-of-Hospital Cardiac Arrest
    • Identifying Locations for Public Access Defibrillators Using Mathematical Optimization
    • Acute Post-Resuscitation Care
    • Is Hypothermia After Cardiac Arrest Effective in Both Shockable and Nonshockable Patients?: Insights From a Large Registry
    • Hypothermia in Comatose Survivors From Out-of-Hospital Cardiac Arrest: Pilot Trial Comparing 2 Levels of Target Temperature
    • Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest: Evaluation of a Regional System to Increase Access to Cooling Circulation
    • Implementation of the Fifth Link of the Chain of Survival Concept for Out-of-Hospital Cardiac Arrest
    • Disclosures
    • Footnotes
    • References
  • Info & Metrics
  • eLetters

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    Most Important Outcomes Research Papers on Cardiac Arrest and Cardiopulmonary Resuscitation
    Karthik Murugiah, Serene I. Chen, Kumar Dharmarajan, Sudhakar V. Nuti, Brian Wayda, Abbas Shojaee, Isuru Ranasinghe and Rachel P. Dreyer for the Editor
    Circulation: Cardiovascular Quality and Outcomes. 2014;7:335-345, originally published March 18, 2014
    https://doi.org/10.1161/CIRCOUTCOMES.114.000957

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    Most Important Outcomes Research Papers on Cardiac Arrest and Cardiopulmonary Resuscitation
    Karthik Murugiah, Serene I. Chen, Kumar Dharmarajan, Sudhakar V. Nuti, Brian Wayda, Abbas Shojaee, Isuru Ranasinghe and Rachel P. Dreyer for the Editor
    Circulation: Cardiovascular Quality and Outcomes. 2014;7:335-345, originally published March 18, 2014
    https://doi.org/10.1161/CIRCOUTCOMES.114.000957
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