Abstract 160: Ethnic differences in the Relationship of theECG QRS Interval to Findings on Cardiac Magnetic Resonance Imaging
Background: QRS prolongation is associated with increased risk of ventricular arrhythmias and cardiac death. Studies have suggested its association with areas of scarring fibrotic tissue on the myocardium from infarction and non-ischemic fibrosis and arrhythmogenesis identified by late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR). Group ethnicity might play role on fibrotic tissue and cardiac conduction. We aimed to evaluate the QRS interval among white, Hispanic and black population by LGE CMR.
Methods: Forty-two patients with CMR performed for different purposes were divided by white, Hispanic and black ethnicity and stratified by age, male gender, heart failure (HF), coronary artery disease (CAD), left ventricle ejection fraction (LVEF) on CMR and presence of any segmental LGE. We then stratified each ethnicity group by the presence or not of LGE and analyzed the QRS interval.
Results: Baseline characteristics were similar among all three groups detailed LVEF were 51%, 42% and 52% for white, black and Hispanic patients, respectively (p=0.07). There was no difference of QRS interval in patients with or without any segmental LGE in white and black population. Hispanic patients with LGE presented with significant prolongation of QRS interval when LGE was present (91 vs. 128; p=0.002).
Conclusion: This is the first analysis of ECG QRS interval among different ethnicities with similar baseline characteristics and preserved cardiac function by LGE on CMR. We have demonstrated that LGE on CMR is associated with a prolonged QRS interval only in a Hispanic population.
Author Disclosures: D. Garcia: None. F.Y. Macedo: None. R.C. Nascimento: None. J. Viles-Gonzalez: None. R. Hendel: None.
- © 2014 by American Heart Association, Inc.