Abstract 311: Risk Factor Profile and Outcome in Young Adults Presenting With Acute Myocardial Infarction Compared to Older Adults.
Background: Management of acute myocardial infarction has improved but preventing the first myocardial infarction in the first place continues to be a challenge. Guidelines for prevention have focused on ‘one-size-fits-all’ approach. With the nation’s changing trends in risk factor profile (Diabetes mellitus, obesity and tobacco use), we aimed to examine the risk factor profile for young adults (<50 years) suffering acute myocardial infarction (AMI) and compared to older adults (>50 years).
Methods: The Nationwide Inpatient Sample (NIS), a part of the Healthcare Cost and Utilization project (HCUP) is the largest publicly available inpatient database designed to provide information on patients discharged from United States community hospitals. Using the NIS database from 2008 to 2010, 374,173 adults with AMI were identified.
Results: Younger adults had a significantly higher incidence of smoking (51% vs. 18.8%; P< 0.001) and obesity (17.3% vs. 9.9%; P<0.001). The rate of hypertension was similar in both groups.
Younger adults were more likely to present with ST elevation myocardial infarction (42 % vs. 27%) and undergo percutaneous revascularization (62% vs. 41%) as compared to older adults.
In-hospital mortality was lower in younger adults presenting with AMI (1.7 % vs. 6.2%) as expected.
Conclusion: 1). Acute MI in the young adult is more likely to present as STEMI.
2). Young adults are more likely to be obese and use tobacco.
3). The results suggest that there is opportunity to improve AMI in the young by focusing on modifiable risk factors.
4). The lower short term mortality may imply that young adults with MI are beset with greater or long standing burden for complications.
Author Disclosures: V. Indramohan: None. R. Hajjali: None. K. Akosah: None.
- © 2014 by American Heart Association, Inc.