Table 4.

Clinical End Points by Infusion Arms for Patients Without Diabetes Mellitus

End PointEDTA Chelation (n=517)Placebo (n=558)Hazard Ratio (95% CI)P Value
Primary end point142 (27%)144 (26%)1.02 (0.81–1.28)0.877
Death55 (11%)43 (8%)1.35 (0.90–2.01)0.137
MI36 (7%)37 (7%)1.03 (0.65–1.64)0.872
Stroke6 (1%)10 (2%)0.65 (0.24–1.80)0.406
Coronary revascularization82 (16%)95 (17%)0.90 (0.67–1.21)0.474
Hospitalization for angina8 (2%)12 (2%)0.71 (0.29–1.74)0.440
Secondary end point61 (12%)61 (11%)1.06 (0.74–1.50)0.760
Cardiovascular death31 (6%)24 (4%)1.37 (0.81–2.34)0.239
  • CI indicates confidence interval; and MI, myocardial infarction.